15 November 2022
Our review article made the cover of the December Issue in Trends in Microbiology!
Phase Separation in Viral Infections
23 September 2022
We have been awarded an EPFL enable grant to further develop our TLC Library Preparation!
We are pleased to share with you the news that EPFL enable will support the project TLC, aiming at showcasing the potential of TLC through proof-of-concept…
TLC Library Preparation
The generation of double-stranded cDNA is a crucial step during NGS library preparation from RNA. Tailing and ligation of cDNA -TLC- presents a novel approach to generate full-length cDNA molecules, offering an alternative to template switch oligos. This work will showcase the potential of TLC throu…
26 July 2022
Ernst Lab on Twitter
“New review article from our lab on phase separation in viral infections! Great collaboration with @wai_lung_ng and many more! Check it out @TrendsMicrobiol https://t.co/OfmwXJBkM6”
Phase separation in viral infections
Viruses rely on the reprogramming of cellular processes to enable efficient viral
replication; this often requires subcompartmentalization within the host cell. Liquid–liquid
phase separation (LLPS) has emerged as a fundamental principle to organize and subdivide
cellular processes, and plays an imp…
replication; this often requires subcompartmentalization within the host cell. Liquid–liquid
phase separation (LLPS) has emerged as a fundamental principle to organize and subdivide
cellular processes, and plays an imp…
14 April 2022
Christina Ernst on Twitter
“🚨 Paper Alert! 🚨
Interested in an easy and reproducible method to measure RNA-protein interactions? Here is some TLC for CLIP! https://t.co/bm8ITyhtzS @ErnstLab_ @epflSV @snsf_ch @HFSP @biorxivpreprint #RNAbindingProteins #RNA #Ambizione #SNSF_Research A thread🧵👇”
Interested in an easy and reproducible method to measure RNA-protein interactions? Here is some TLC for CLIP! https://t.co/bm8ITyhtzS @ErnstLab_ @epflSV @snsf_ch @HFSP @biorxivpreprint #RNAbindingProteins #RNA #Ambizione #SNSF_Research A thread🧵👇”
Efficient and sensitive profiling of RNA-protein interactions using TLC-CLIP
RNA-binding proteins are instrumental for post-transcriptional gene regulation, yet transcriptome-wide methods to profile RNA-protein interactions remain technically challenging. We present an improved library preparation strategy for cross-linking and immunoprecipitation (CLIP) that involves tailin…
20 October 2021
EPFL life scientist awarded Ambizione grant
Dr Christina Ernst at EPFL’s School of Life Sciences has been awarded an Ambizione grant for research in Molecular Biology.
02 September 2021
